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March 2010

Volume 14 Issue 2

The Canadian Light Source: A Leading Light for Macromolecular Crystallography
By Matthew Dalzell
Over the last 20 years synchrotron light sources have become a valuable tool for understanding the structure and function of biological macromolecules, particularly in the fields of proteomics and pharmaceutical research. Located on the campus of the University of Saskatchewan in Saskatoon, the Canadian Light Source (CLS), Canada’s national synchrotron facility, is establishing itself as a leading light for macromolecular crystallography with its Canadian Macromolecular Crystallography Facility (CMCF).

Influence of Physical Parameters on the Dispensed Volume of Air-Cushion Pipette
By Kornelia Ewald
Physical parameters play an essential role for dispensing with air-cushion pipettes. Results of analysis are directly impacted by the density of the pipetted liquid. Also, parameters like vapour pressure, viscosity and, in particular, temperature differences have to be regarded as well.