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Volume 10, Issue 10

Molecular Diagnostic Assays: Leading a High Value Evolution
By John C. Schafer

Clinical laboratory testing today is on the verge of significant change. Due, in part, to the sequencing of the human genome, molecular diagnostic assays are beginning to appear on the testing menus of laboratories around the world with a potential for fundamentally impacting health care.

Risk Management Program and Biologics
By John Leombruno

The traditional method of identifying the potential toxicity of small molecule pharmaceuticals is quite exhaustive and consists of several investigations required by regulatory agencies, including in-vitro assays, multispecies animal toxicity studies, single dose safety/pharmacokinetic studies in healthy volunteers, short term multiple dose safety and efficacy studies in diseased subjects, reproductive toxicity studies, genotoxicity studies, carcinogenicity studies, etc.

Build it and Fill it
By Shawn Lawrence

Managing money is his expertise while the world of life sciences is his passion. As president and CEO of LAB Research Inc. (LRI), a global non-clinical contract research organization, Luc Mainville gets to enjoy the pleasures of doing something he loves while at the same time something he's good at.

Engineering Better Health Care
By Mike Pettapiece

There are engineers building vehicles with a difference: tiny devices, some of them ingestible like a pill that will travel through the human body. These biosensors and imaging tools will differentiate between healthy cells and abnormal ones, be able to 'read' tissues without requiring numerous biopsies, and micro-sample the tissues and surrounding fluid.